EFFECT OF FISH OIL ON SERUM LIPID TISSUE FATTY ACID COMPOSITION CHOLESTEROL AND OF JUVENILE RAT

The effect of fish oil containing eicosapentaenoic acid （EPA) and docosahexaenoic acid (DHA)on serum lipid, cholesterol and fatty acid compo-sition of juvenile rat was studied. The experimental rats (Spraglue dawley)were divided into three groups with 7 animals each for female and male per group. In the basal diet soybean oil, fish oil and fish oil concentrate were admixed for Group A, Group B and Group C, respectively. After 4 weeks feeding, the contents of serum lipid and cholesterol. in Group B and C were lower than those in Group A (P<0.05).By fatty said assay it showed that the levels of EPA and DHA in the tissues of Group B and C were higher than those in Group A, whereas the contents of arachidonic and docosatetraenoic acid in the tissues of Group A were much higher than those in Group B and C. Interestingly, the analytical results showed that in the rat brain of Group B and C was only DHA well higher in content than that in Group A,and therefore DHA in fish oil would be possible to play an impor-tent role in eugenics. No appreciable difference in body weight gain, weight ratio of viscera to body，total serum protein and alkaline phosphotase among these three groups was observed (P>0.05).